As the Cannabis market grows for both medical and recreational use, so does the requirement for standardized quality control within the industry. With regards to Cannabis quality control there are numerous things to consider, from moisture content to pesticide use.
Moisture Content – Cannabis flower moisture content ought to be tested and controlled to: minimize the potential risk of mold formation; control microbiological levels; ensure proper drying, curing and storage conditions; and support product shelf life. Some manufacturing processes for marijuana quality assurance plan also need a certain water content inside the starting material.
Terpenoids and Cannabinoids Analysis
The degree of terpenoids and cannabinoids within the starting material determines the most appropriate industrial processing method and which final cannabis product will likely be manufactured. This analysis is normally performed using LC-MS (Liquid Chromatography Mass Spectrometry) or GC (Gas Chromatography). LC-MS and GC demand a flow of inert gas like hydrogen or nitrogen, each of which can be simply supplied using a gas generator. Uncover more concerning the Peak Scientific variety of gas generators for GC & LC-MS here.
Pesticides and Herbicides – As with other agricultural crops and merchandise intended for human consumption, Cannabis plants needs to be tested for herbicides and pesticides. Detecting pesticides and herbicides can be difficult because of the complexity of cannabis material. GCMS (Gas Chromatography Mass Spectrometry) is usually used for this specific purpose.
Microbiological Screening – Medical Cannabis is frequently utilized for HIV and cancer patients where the patient’s immunity mechanism has been compromised. Therefore, high microbial levels or pathogenic micro-organisms might be life threatening. It is necessary then that several Mycotoxins and fungus types ought to be detected included in cannabis quality control and release specifications.
Residual Solvents – Where solvents happen to be used included in Cannabis product processing, solvent residuals within the final products needs to be tested to make sure that they satisfy the accepted criteria. The FDA has published zvqtob criteria for residual solvents in APIs for pharmaceutical use.
Heavy Metals – Like various other plants, Cannabis draws metals from your earth. It really is therfore necessary to test for Mercury, Lead, Arsen and Cadmium.
Cannabinoid Concentration – Concentration ranges for cannabinoids including THC,THCa, CBD, CBDa, CBN, CBC, CBG should match the ranges specified on the product label, based on product usage purpose, patient’s medical problem, age etc. Cannabinoid concentrations may be tested using LC-MS (Liquid Chromatography Mass Spectrometry) and HPLC (Good Performance Liquid Chromatography) . There are an array of Peak Scientific nitrogen gas generators designed particularly for LC-MS, available here.
Terpene Concentration – Terpenes increase cannabinoids’ therapeutic effects and are acknowledged to get their own health and fitness benefits, in addition they contribute to Cannabis taste and aroma. They could be detected using GC.
Taking all of the above into consideration, it is clear that there exists a necessity for standarized procedures for every step of the Cannabis analysis and testing process so that you can guarantee safe use. The safest method to supply cannabis testing laboratories with gas for their LC-MS and GC is by gas generators, which do not present the safety and health risks associated with gas cylinders.